· It's probably much easier to do Peru independently than it used to be. But it is a big country and there is a lot of logistical organisation to do if you want to see the incredible variety it has to offer. The hassle of trying to arrange transport and making sure you don't get ripped-off is probably not worth it unless you intend to spend two or three months out there.

Last September, my girlfriend and I spent three weeks in Peru and Bolivia with Journey Latin America (020-8747 8315, journey latinamerica.co.uk). Its trips are organised into 'Tours' and 'Journeys', and I would recommend the latter. 'Tours' use western-standard hotels and air-conditioned coaches, but 'Journeys' use local transport and more down-to-earth accommodation. You have a local guide but plenty of freedom to do your own thing.

Jonathan Crewe

· I recently escorted my elderly parents, both of whom have slight health problems, on a trip through South America. There is no reason why moderate ill health should preclude independent travel in that area.

Spanish language skills will ease independent travel immensely. Taxis in Peru and Bolivia are very cheap, and can be hired for a whole day at minimal cost, so walking on excursions can easily be kept to a minimum. Ensure you agree all taxi fares in advance and always barter.

Remember that any health problems that relate to 'pre-existing conditions' will not be covered on most standard travel insurance policies.

Jon Dillon

· Last autumn a friend and I - both female and 50ish - travelled in Bolivia before going south to Argentina and then Uruguay. In Bolivia, you will find it pretty easy to get around as the local travel agent offices sell bus tickets or offer short trips. As local people use the long distance buses to travel around, there is plenty of choice and it's fascinating experience being on one because of all the sellers that get on and the stops you make at local markets etc.

We felt safe and found people helpful and friendly but the usual caveats apply - be cautious with your stuff; don't take too much of anything you can buy locally (shopfront laundries will wash and dry your clothes in a few hours); don't expect every place you arrive at to have late-night food available.

Gail Sanderson

· The 'weak' knees should not be a great problem, although I would not recommend the Inca Trail to Machu Picchu - it is a gruelling four days of walking at high altitude. Instead, take the train to Aguas Calientes and then a bus to Machu Picchu.

Meera Chand

· The free LATA Guide from the Latin American Travel Association (020-8715 2913, lata.org) lists all its member tour operators, airlines, hotels, tourist boards and guide books featuring Peru and Bolivia as well as 23 other regions. The Guide also offers numerous tips on what to do, where to go and what to eat and drink.